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Boehm syndrome : ウィキペディア英語版 | Boehm syndrome Boehm Syndrome is a symptom-specific map-dot-fingerprint dystrophy of the cornea. The epithelium is separated from the stroma by a membrane. In map-dot-fingerprint dystrophy, this membrane develops abnormally exhibiting a map-like appearance or perhaps opaque dots. Sometimes lines are formed that resemble small fingerprints. In some cases, this irregular structure can lead to painful epithelial erosions. ==Signs and symptoms== In Boehm Syndrome, recurrent epithelial erosions occur ''only when the eyelids are opened after some period of sleep''. Recurrent corneal erosions may happen at any time of night or day. Boehm Syndrome does not. It occurs only when the inside of the eyelid tears away epithelial cells after minutes or hours of sleep. This may expose nerve endings, causing moderate to severe pain for hours or days. Once the erosions begin, even periods of brief sleep can exacerbate the problem. Patients may describe the sensation as "''my eyelids stick to my eyes when I try to open them, which is immediately followed by intense pain''". In some cases, this syndrome may disappear after one or more episodes. For others, it may be a lifelong disease.
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